In our project we aim to integrate 21st century skills working through real experiments combining content, instruction, literacy, and different learning skills. Students may learn to use the tools and conventions of science. They may develop skills in using scientific equipment correctly and safely, making observations, taking measurements, and carrying out well-defined scientific procedures. In a experimental classroom acts like a vessel of 21st-century skills such as critical thinking, creative thinking, collaboration, and communication will be. At the same time, since digital technology and connectivity are fundamental aspects of learning, students also have the opportunity to expand their 21st-century information, media, and technology literacy skills. Another benefit of experimental classroom is that students control their education and shift the learning dynamic from teacher to student-centric. They learn to learn.